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How do muscles make us strong? Find out at IF Oxford Science & Ideas Festival

Public Engagement

If you've ever wondered about the role of the muscle, come and meet us at IF Oxford - the Oxford science and ideas Festival on Saturday 8th & 15th October, when our researchers will be challenging members of the public to play our "Muscle Switch" game and exploring why strength differs between us.

It’s not just Covid: the triple threat that could overwhelm the NHS this winter - Andrew Pollard

COVID-19 Vaccinology

A severe flu outbreak or new coronavirus variant could prove catastrophic for a health service already on its knees

Study raises hope of pre-school type 1 diabetes screening programme

Children's Health Research

Researchers in Oxford have launched the first UK study in the general population to test for early markers of type 1 diabetes before children develop symptoms or need insulin.

Oxford scientists honoured with eight Royal Society Awards

Each year, the Royal Society recognises exceptional research achievements through a series of prestigious medals and prizes named after great scientists of the past. Eight of the 2021-22 awards, announced today, honour Oxford University researchers for their outstanding contributions to science and medicine.

Promising Marburg vaccine yet to be tested on humans due to lack of funding

Oxford University’s Professor Teresa Lambe, the designer of the vaccine, fears Marburg disease is ‘now being seen in places where it’s never been seen before’

Oxford vaccine saved most lives in its first year of rollout

When the University of Oxford developed a vaccine that was effective against COVID-19, ensuring that it could be rolled out globally and in perpetuity for low- and middle-income countries was of paramount importance.

IDRM officially opens in Oxford

A celebration for the opening of our Institute took place on Tuesday 12 July 2022 in the IMS-Tetsuya Nakamura Building, which was supported by a very generous donation from Dr Tetsuya Nakamura, Chief Director of Itabashi Medical System Group (IMS-Group), and substantial fund-raising from the British Heart Foundation (BHF).

Early life infection increases sensitivity to pain in newborn babies

Researchers from Oxford’s Department of Paediatrics have discovered that infection can increase a baby’s sensitivity to pain, which may last longer than the infection.

Novel all-in-one vaccine developed to tackle future coronavirus threats

COVID-19 Vaccinology

Up to $30 million in funding has been announced by the Coalition for Epidemic Preparedness Innovations (CEPI) to bring a new nanoparticle vaccine offering protection against a range of coronaviruses to clinical trial.

Professor Sir Andrew Pollard Awarded the James Spence Medal in 2022

The James Spence Medal is the highest honour awarded by the RCPCH, and is awarded for outstanding contributions to the advancement of knowledge and understanding in paediatrics and child health.

Department of Paediatrics celebrates 50-year anniversary

On Wednesday 15th June, the Department of Paediatrics invited its members of staff and selected guests to join them at the Oxford University Museum of Natural History to embark on special evening of celebrations, commemoration, and entertainment.

A simple test at birth could positively transform the life of 70 families per year in the UK and save the NHS £280 every minute.

It is a tragedy for a child to be diagnosed with a severe and disabling lifelong medical condition. But in addition to the child’s difficulties and suffering and the emotional cost to their family, such maladies can also create a significant financial cost to both the family and to society; whether due to the cost of treatments, the expense of medical equipment and home adaptations, or indeed the loss of a family’s productivity.

20 Minutes of Vigorous Daily Exercise Can Keep Teens' Doctors Away

Teens should exercise vigorously for at least 20 minutes per day to reap increased cardiorespiratory fitness (CRF), according to a cross-sectional study from the U.K.

Com-COV vaccine study to research third dose booster options for 12-to-15-year-olds

Researchers running the University of Oxford-led Com-COV programme have launched a further study of COVID-19 vaccination schedules in young people aged 12 to 15 – with a focus on assessing different options for a third dose booster vaccination.

AR cooperates with SMAD4 to maintain skeletal muscle homeostasis

Neuromuscular Diseases

Skeletal muscle, which accounts for over 40% of the total mass in healthy individuals, plays a central role in maintenance of organismal homeostasis. Conversely, muscle atrophy upon acute and chronic conditions, ranging from genetic muscular dystrophy to critical illnesses, cachexia and sarcopenia, significantly correlates with levels of disability and is an important predictor of mortality. Despite the urgent medical need, treatments able to efficiently counteract muscle loss are lacking due to an incomplete understanding of the underlying intricate molecular mechanisms of regulation.

Developmental dynamics of the neural crest–mesenchymal axis in creating the thymic microenvironment

Immunology

A new paper from researchers at the Department of Paediatrics and the Nuffield Department of Clinical Neurosciences has shown that fibroblasts in the thymus, often considered simply as dull “structural” cells, are much more complex than previously thought.

Fourth COVID-19 vaccine dose provides stronger immunity boost than third dose, shows UK study

COVID-19 Vaccinology

COVID-19 vaccines given as fourth doses in the UK offer excellent boosting immunity protection, according to the latest results from a nationwide NIHR-supported study.

Oral paratyphoid vaccine to begin human trials

Vaccinology

The University of Oxford in collaboration with the University of Maryland School of Medicine (UMSoM) has begun recruiting for a Phase I/II trial of a new paratyphoid vaccine in human volunteers in Oxford.

Oxford scientist named Australian of the Year in the UK

Awards & Appointments COVID-19 Public Engagement Vaccinology

The Oxford Vaccine Group’s Lead Statistician, Professor Merryn Voysey, received the prestigious Australian of the Year in the UK award at a gala dinner recently.

KEMRI-Wellcome Trust Researchers Awarded Fellowships

The KEMRI Wellcome Trust Research Programme (KWTRP) is based within the KEMRI Centre for Geographic Medical Research – (Coast). The core activities are funded by the Wellcome Trust. They conduct integrated epidemiological, social, laboratory and clinical research in parallel, with results feeding into local and international health policy.

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