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Featured publication: Advances in oligonucleotide drug delivery

Neuromuscular Diseases Publication

Oligonucleotides - short DNA or RNA molecules - have great therapeutic application for a range of diseases. Yet, their potential has not been fully unleashed because of challenges linked to efficient delivery. Read more to find out about recent developments in oligonucleotide modifications, and the platforms that may be used to deliver them to target sites.

Typhoid vaccine project wins Vice-Chancellor award

Awards & Appointments Vaccinology

Congratulations to Professor Andrew Pollard who is the Winner of the Policy Engagement category in the Vice-Chancellor Innovation Awards 2020 for his work on Global policy on typhoid vaccines through research at Oxford!

New study reveals Oxford coronavirus vaccine produces strong immune response

COVID-19

A team of scientists at Oxford Vaccine Group (Department of Paediatrics) and Oxford University’s Jenner Institute has taken the next step towards the discovery of a safe, effective and accessible vaccine against coronavirus.

Ebola vaccine approved for use by the European Commission

Vaccinology

The European Commission has granted Marketing Authorisation to Janssen for a new Ebola vaccine, developed in partnership with the University of Oxford.

The Duke of Cambridge visits Oxford Vaccine Centre

COVID-19 Vaccinology

The Duke of Cambridge visits the University of Oxford’s Oxford Vaccine Centre, to learn more about their work to establish a viable vaccine against COVID-19.

AstraZeneca to supply Europe with up to 400 million doses of Oxford University’s vaccine at no profit

COVID-19 Clinical Trials Vaccinology

AstraZeneca has reached an agreement with Europe’s Inclusive Vaccines Alliance (IVA), spearheaded by Germany, France, Italy and the Netherlands, to supply up to 400 million doses of the University of Oxford’s COVID-19 vaccine, with deliveries starting by the end of 2020.

Alice in Typhoidland wins film trophy

Bristol Science Film Festival awarded the Professional Science Fact Film Prize to "The Adventures of Alice in Typhoidland" co-created by the Oxford Vaccine Group.

Coronavirus: is it safe for children to return to school?

COVID-19 Children's Health General Parents & Carers

Stéphane Paulus and Else Bijker explore the topic in their article for The Conversation.

Oxford COVID-19 vaccine to begin phase II/III human trials

COVID-19 Clinical Trials Vaccinology

Oxford Vaccine Group researchers have begun recruiting for the next phase in human trials of a COVID-19 vaccine in human volunteers.

Paediatrics professor honoured by the Academy of Medical Sciences

The Academy of Medical Sciences, the independent body in the UK representing the diversity of medical science, has announced the election of fifty new Fellows, including Professor Matthew Wood from the Department of Paediatrics.

HIV study explains immunological differences between sexes

HIV

How can researching a cohort of infants from KwaZulu-Natal in South Africa help explain differing HIV susceptibility of males and females? Professor Philip Goulder, head of the HIV Research Group, discusses the Baby Cure study.

Landmark partnership announced for development of COVID-19 vaccine

COVID-19

The University of Oxford has today announced an agreement with the UK-based global biopharmaceutical company AstraZeneca for the further development, large-scale manufacture and potential distribution of the COVID-19 vaccine candidate currently being trialled by the Oxford Vaccine Group.

Oxford COVID-19 vaccine begins human trial stage

COVID-19 Recruitment Research Vaccinology

University of Oxford researchers have begun testing a COVID-19 vaccine in human volunteers in Oxford today. Around 1,110 people will take part in the trial, half receiving the vaccine and the other half (the control group) receiving a widely available meningitis vaccine.

Paediatrics project receives funding to assess novel coronavirus infection rates in children and teenagers across the UK

Awards & Appointments COVID-19 Vaccinology

A multi-site project, called ‘What’s the STORY?’ has received funding from UK Research and Innovation (UKRI) to assess novel coronavirus infection rates in children and teenagers across the UK. Given the importance of this study to the national Covid-19 response it has been deemed a priority study for the National Institute for Health Research’s (NIHR) Urgent Public Health Response.

Funding for new COVID-19 studies awarded to OVG's project on infectious disease immunity in children

Awards & Appointments COVID-19 Research Vaccinology

Five projects from across Oxford University's Medical Sciences Division, including a project led by Professor Matthew Snape from the Oxford Vaccine Group, are among twenty-one new studies into the novel coronavirus which have been funded by the UK government.

Visualising COVID-19 outbreak

COVID-19 Neuroimaging Research Research Methods

Paediatric Neuroimaging researcher provides real-time case information on epidemiological data from the COVID-19 outbreak.

Oxford COVID-19 vaccine programme opens for clinical trial recruitment

COVID-19 Research Vaccinology

University of Oxford researchers working in an unprecedented vaccine development effort to prevent COVID-19 have started screening healthy volunteers (aged 18-55) today for their upcoming ChAdOx1 nCoV-19 vaccine trial in the Thames Valley Region. The vaccine based on an adenovirus vaccine vector and the SARS-CoV-2 spike protein is already in production but won’t be ready for some weeks still.

Sharing the benefits

Athena Swan Neuroimaging Parents & Carers University

At the beginning of the year our family leave policies were updated. Employees can now take up most of our family leave schemes from the first day of employment, meaning that more parents can now enjoy the benefits of our generous provisions. Hayriye Cagnan from the Nuffield Department of Clinical Neurosciences, and husband Eugene Duff from the Department of Paediatrics, discuss their experience of shared parental leave following baby Ida’s arrival ten months ago.

COVID-19 vaccine development

COVID-19 Research Vaccinology

A vaccine candidate for COVID-19 has been identified by researchers from the Oxford Vaccine Group and Oxford's Jenner Institute.

Communicating the messages of extracellular vesicles to the wider public

Public Engagement

Wood Group researchers in the Department of Paediatrics collaborate with DPAG's Denis Noble to produce innovative podcast talks on a prominent global platform, the Future Tech Podcast. Following the release of the final podcast talk in February 2020, we chart the story leading to these innovative pieces of public engagement.

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