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Oxford scientists launch first-in-human vaccine trial for deadly Marburg virus

Clinical Trials Recruitment Research Vaccinology

Scientists at the University of Oxford have launched a new clinical trial to test a vaccine to protect people against deadly Marburg virus.

New discovery renews hope for thousands with neurodevelopment disorders

Children's Health Publication Research

A global collaboration led by scientists at the University of Oxford has discovered that genetic variants in a specific gene cause a rare neurodevelopmental disorder (NDD). NDD is a collective term for severe impairments in how the brain functions that impact learning, behaviour, speech, and movement. Most NDDs are thought to be genetic and caused by changes to DNA, however, to date, around 60% of individuals with these conditions do not know the specific DNA change that causes their disorder.

New trial launches for two-in-one vaccine to prevent RSV and hMPV

Children's Health Clinical Trials Research Vaccinology

Scientists at the University of Oxford have launched a phase 1 study to test two investigational mRNA vaccines: one for both respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) and a second for RSV alone in infants aged five to eight months old. The vaccines are being developed by Moderna.

Research shows early life immunity increases HIV cure/remission in male infants

Children's Health HIV Publication Research University

New research published by scientists at the University of Oxford, the University of KwaZulu-Natal and the Africa Health Research Institute in South Africa, and the Ragon Institute of Mass General, MIT and Harvard, USA, shows that male infants are more likely to achieve HIV cure/remission than females.

GOSH Charity co-funds two data-driven projects to advance research into childhood cancers

Awards & Appointments Children's Health Research

Great Ormond Street Hospital (GOSH) Charity has joined forces with Cancer Research UK (CRUK) to co-fund two projects that will use data science to advance research into childhood cancers.

New research assesses the function of a major genetic cause of neurodevelopmental disorders

Department Publication Research

New research, published today, has defined the functional impacts of hundreds of variants in a gene that is a major cause of neurodevelopmental disorders.

Professor Teresa Lambe OBE elected to the Fellowship of the Academy of Medical Sciences

Awards & Appointments Department Public Engagement Vaccinology

Professor Teresa Lambe OBE, Calleva Head of Immunology at the Oxford Vaccine Group, and Principal Investigator at the Pandemic Sciences Institute, has been elected a Fellow of the Academy of Medical Sciences, one of the most prestigious awards in the field.

Professor Sir Andrew Pollard elected to the Fellowship of the Royal Society

Awards & Appointments Department Research

Professor Sir Andrew Pollard, Director of the Oxford Vaccine Group at the Department of Paediatrics, and Ashall Professor of Infection and Immunity has today been elected a Fellow of the Royal Society.

Ground-breaking study reveals how COVID-19 vaccines prevent severe disease

COVID-19 Clinical Trials Publication Research Research Methods Vaccinology

A landmark study by scientists at the University of Oxford, has unveiled crucial insights into the way that COVID-19 vaccines mitigate severe illness in those who have been vaccinated.

How the Information Security Office and the National Cyber Security Centre keeps Oxford's research secure post-pandemic

COVID-19 Department General University

Oxford University's Information Security Office (InfoSec) invited the NCSC to Oxford to thank them for the work they did that kept Oxford’s vaccine research secure.

Oxford hosts Belgian vaccine experts

Department General Vaccinology

Researchers from Oxford Vaccine Group and the Pandemic Sciences Institute welcomed a delegation of vaccine researchers from Belgium to further UK-Belgian collaboration on vaccine development and manufacture.

Advancing a malaria vaccine for better global health outcomes

Department General Vaccinology

Professor Sue Ann Costa Clemens CBE, Chair of Global Health at the Department of Paediatrics and Head of Oxford Latam Research Group – a collaboration between Oxford and Brazil, aimed at strengthening our commitment to global health – met with His Excellency Antonio Patriota, Brazilian Ambassador to the UK, to discuss the co-development of a Malaria vaccine and advance public health outcomes in Brazil.

New trial to study how the human immune system adapts to ‘tolerate’ malaria parasites

Clinical Trials Research Research Methods Vaccinology

Scientists at the University of Oxford and the University of Edinburgh have launched a pioneering study that examines how the immune system responds to repeated malaria infections. The BIO-004 study is being run in partnership between the Department of Biochemistry (Draper Lab, based in the Kavli Institute for Nanoscience Discovery), the University of Edinburgh (Spence Lab, Institute of Immunology and Infection Research) and the Oxford Vaccine Group (part of the Department of Paediatrics). BIO-004 will provide a unique insight into how the immune system adapts over the first few malaria infections of life, learning to tolerate malaria parasites and developing natural immunity to severe illness.

Research shows comforting babies eases parental stress in painful procedures

Neuroimaging Parents & Carers Research

The Neuroimaging Group, at the Department of Paediatrics, in collaboration with Bliss, the charity for babies born premature or sick, has launched a new suite of information resources for parents of neo-nates, designed to make them feel more confident about being involved in the care of their babies.

Student wins award for Individual Excellence in Clinical Data Management

Awards & Appointments Clinical Trials Department

Yama Mujadidi, DPhil student and Clinical Trials IT & Development Lead at the Oxford Vaccine Group, has been awarded the prize for Individual Excellence by the Association for Clinical Data Management.

Novartis Global Scholar Program award for Neuromuscular team

Awards & Appointments Department Neuromuscular Diseases Research

Many congratulations to Associate Professor Carlo Rinaldi and Senior Postdoctoral Scientist Antonio Garcia-Guerra, who have been awarded the Novartis Global Scholar Program (NGSP) for 2023.

Shining a light on Rare Disease

Department General Public Engagement

The chapel facade of Magdalen College, Oxford, was awash with colour this evening to raise awareness of the plight of those living with rare disease.

Clinical Lecturer in Paediatrics selected as finalist for the MRC Impact Prize 2023: Early Career Impact

Awards & Appointments Department Public Engagement Research

Dr Michelle Fernandes, a Clinical Lecturer at the Department of Paediatrics, Research Fellow at the Nuffield Department of Women’s & Reproductive Health, and Associate Fellow at Green Templeton College has been selected as a finalist for the Medical Research Council (MRC) Impact Prize 2023, for her cross-disciplinary research in international early child development.

New animation series to support parents of premature infants

Children's Health Department Neuroimaging Parents & Carers Public Engagement Research

Professor Caroline Hartley, Principal Investigator, and Dr Marianne van der Vaart Postdoctoral Researcher, in the Paediatric Neuroimaging Group at the Department of Paediatrics, have today launched a series of animations aimed at improving parental understanding of brain development in premature infants, and the effect it has on breathing and apnoeas (the cessation of breathing).

New protein discovery sheds light on complexity of genetic regulation

Department Publication Research

Scientists at the Department of Paediatrics have discovered a new pathway that the human body uses to silence transposable elements or ‘jumping genes’. Dr. Rebecca Berrens, Principal Investigator in the Transposon Group, has published research into the piRNA pathway, a key process our body uses to keep these transposable elements in check.

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