Search results (102)
« Back to NewsNew research identifies autoimmunity against a key anti-inflammatory regulator in inflammatory bowel disease
4 August 2024
Clinical Trials Department Gastroenterology Immunology Publication Research Research Methods University
A ground-breaking study, published by the New England Journal of Medicine, has identified a new disease-inducing mechanism for inflammatory bowel disease (IBD) in which the immune system attacks its own regulatory function.
Oxford scientists launch first-in-human vaccine trial for deadly Marburg virus
12 July 2024
Clinical Trials Recruitment Research Vaccinology
Scientists at the University of Oxford have launched a new clinical trial to test a vaccine to protect people against deadly Marburg virus.
New discovery renews hope for thousands with neurodevelopment disorders
12 July 2024
Children's Health Publication Research
A global collaboration led by scientists at the University of Oxford has discovered that genetic variants in a specific gene cause a rare neurodevelopmental disorder (NDD). NDD is a collective term for severe impairments in how the brain functions that impact learning, behaviour, speech, and movement. Most NDDs are thought to be genetic and caused by changes to DNA, however, to date, around 60% of individuals with these conditions do not know the specific DNA change that causes their disorder.
New trial launches for two-in-one vaccine to prevent RSV and hMPV
12 July 2024
Children's Health Clinical Trials Research Vaccinology
Scientists at the University of Oxford have launched a phase 1 study to test two investigational mRNA vaccines: one for both respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) and a second for RSV alone in infants aged five to eight months old. The vaccines are being developed by Moderna.
Research shows early life immunity increases HIV cure/remission in male infants
10 June 2024
Children's Health HIV Publication Research University
New research published by scientists at the University of Oxford, the University of KwaZulu-Natal and the Africa Health Research Institute in South Africa, and the Ragon Institute of Mass General, MIT and Harvard, USA, shows that male infants are more likely to achieve HIV cure/remission than females.
GOSH Charity co-funds two data-driven projects to advance research into childhood cancers
29 May 2024
Awards & Appointments Children's Health Research
Great Ormond Street Hospital (GOSH) Charity has joined forces with Cancer Research UK (CRUK) to co-fund two projects that will use data science to advance research into childhood cancers.
New research assesses the function of a major genetic cause of neurodevelopmental disorders
22 May 2024
Department Publication Research
New research, published today, has defined the functional impacts of hundreds of variants in a gene that is a major cause of neurodevelopmental disorders.
Professor Sir Andrew Pollard elected to the Fellowship of the Royal Society
16 May 2024
Awards & Appointments Department Research
Professor Sir Andrew Pollard, Director of the Oxford Vaccine Group at the Department of Paediatrics, and Ashall Professor of Infection and Immunity has today been elected a Fellow of the Royal Society.
Ground-breaking study reveals how COVID-19 vaccines prevent severe disease
3 May 2024
COVID-19 Clinical Trials Publication Research Research Methods Vaccinology
A landmark study by scientists at the University of Oxford, has unveiled crucial insights into the way that COVID-19 vaccines mitigate severe illness in those who have been vaccinated.
New trial to study how the human immune system adapts to ‘tolerate’ malaria parasites
18 March 2024
Clinical Trials Research Research Methods Vaccinology
Scientists at the University of Oxford and the University of Edinburgh have launched a pioneering study that examines how the immune system responds to repeated malaria infections. The BIO-004 study is being run in partnership between the Department of Biochemistry (Draper Lab, based in the Kavli Institute for Nanoscience Discovery), the University of Edinburgh (Spence Lab, Institute of Immunology and Infection Research) and the Oxford Vaccine Group (part of the Department of Paediatrics). BIO-004 will provide a unique insight into how the immune system adapts over the first few malaria infections of life, learning to tolerate malaria parasites and developing natural immunity to severe illness.
Research shows comforting babies eases parental stress in painful procedures
8 March 2024
Neuroimaging Parents & Carers Research
The Neuroimaging Group, at the Department of Paediatrics, in collaboration with Bliss, the charity for babies born premature or sick, has launched a new suite of information resources for parents of neo-nates, designed to make them feel more confident about being involved in the care of their babies.
Novartis Global Scholar Program award for Neuromuscular team
6 March 2024
Awards & Appointments Department Neuromuscular Diseases Research
Many congratulations to Associate Professor Carlo Rinaldi and Senior Postdoctoral Scientist Antonio Garcia-Guerra, who have been awarded the Novartis Global Scholar Program (NGSP) for 2023.
Clinical Lecturer in Paediatrics selected as finalist for the MRC Impact Prize 2023: Early Career Impact
29 February 2024
Awards & Appointments Department Public Engagement Research
Dr Michelle Fernandes, a Clinical Lecturer at the Department of Paediatrics, Research Fellow at the Nuffield Department of Women’s & Reproductive Health, and Associate Fellow at Green Templeton College has been selected as a finalist for the Medical Research Council (MRC) Impact Prize 2023, for her cross-disciplinary research in international early child development.
New animation series to support parents of premature infants
27 February 2024
Children's Health Department Neuroimaging Parents & Carers Public Engagement Research
Professor Caroline Hartley, Principal Investigator, and Dr Marianne van der Vaart Postdoctoral Researcher, in the Paediatric Neuroimaging Group at the Department of Paediatrics, have today launched a series of animations aimed at improving parental understanding of brain development in premature infants, and the effect it has on breathing and apnoeas (the cessation of breathing).
New protein discovery sheds light on complexity of genetic regulation
21 February 2024
Department Publication Research
Scientists at the Department of Paediatrics have discovered a new pathway that the human body uses to silence transposable elements or ‘jumping genes’. Dr. Rebecca Berrens, Principal Investigator in the Transposon Group, has published research into the piRNA pathway, a key process our body uses to keep these transposable elements in check.
Associate Professor Carlo Rinaldi awarded prestigious Clinical Fellowship
16 February 2024
Awards & Appointments Department Neuromuscular Diseases Research
Associate Professor Carlo Rinaldi, a Consultant Neurologist and Clinician Scientist at the Department of Paediatrics, has been awarded the prestigious UKRI MRC Senior Clinical Fellowship for 2024.
Oxford University professors on the record with their contribution to the fight against cancer for this World Cancer Day
4 February 2024
Department Haematology Research University
This World Cancer Day, four Principal Investigators from the University of Oxford, including Andi Roy, Professor of Paediatric Haematology at the Department of Paediatrics, talk candidly about their work and how they’re helping the fight against cancer.
MDUK Oxford Neuromuscular Centre celebrates five year anniversary
31 January 2024
Clinical Trials Department Neuromuscular Diseases Research
The Department of Paediatrics at the University of Oxford is celebrating the five-year anniversary of a partnership with MDUK. Founded in January 2019, the MDUK Oxford Neuromuscular Centre was set up to drive the development of new therapies and treatments and increase the capacity of clinical trials for muscle wasting and weakening conditions in the UK.
First in-human vaccine trial for Nipah virus
11 January 2024
Clinical Trials Immunology Research Vaccinology
The University of Oxford has launched a new clinical trial to test a vaccine against the deadly Nipah virus.
OVG receives £7.8 million in research funding to fight pandemic and epidemic threats
12 December 2023
Oxford Vaccine Group (OVG), which led the rapid clinical development of the Oxford vaccine in COVID-19 in the pandemic, has been awarded a total of £7,788,783 by UK Aid for research into the prevention of five dangerous diseases with epidemic or pandemic potential.