12 August 2020
Oligonucleotides - short DNA or RNA molecules - have great therapeutic application for a range of diseases. Yet, their potential has not been fully unleashed because of challenges linked to efficient delivery. Read more to find out about recent developments in oligonucleotide modifications, and the platforms that may be used to deliver them to target sites.
7 November 2019
A new wearable ‘bike helmet’ style brain scanner, that allows natural movement during scanning, has been used in a study with young children for the first time. This marks an important step towards improving our understanding of brain development in childhood.
11 September 2019
Collaborative research between teams from the Department of Paediatrics and the Institut de Myologie shows how antisense oligonucleotides can penetrate muscles to treat myotonic dystrophy type 1, a rare muscle disease.
24 June 2019
PBS features Daniel O'Connor's research on how children's genetic profiles affect their immunity.
13 February 2019
In the latest issue of the Blueprint, Shaunna Latchman meets Professor of Paediatric Neuroimaging, Rebeccah Slater to discuss the Paediatric Neuroimaging Group and find out why a gentle touch really does goes a long way.
22 August 2016
A study from Oxford and Basel universities may point the way to maintaining our immune systems as we get older.
18 August 2016
It is difficult to test whether painkillers work for very young children and we often don't know the best dose to give. But if Professor Rebeccah Slater and her research team at Oxford are successful we may find alternative ways to measure pain in babies and may eventually be able to offer babies some better options to soothe their pain.
13 August 2015
Researchers from Oxford University's Department of Paediatrics have successfully completed the first human trial of a vaccine for a common virus that is particularly dangerous to infants.
21 April 2015
The brains of babies ‘light up’ in a very similar way to adults when exposed to the same painful stimulus, a pioneering Oxford University brain scanning study has discovered. It suggests that babies experience pain much like adults.
1 December 2014
The rapid evolution of HIV, which has allowed the virus to develop resistance to patients' natural immunity, is at the same time slowing the virus' ability to cause AIDS, according to new research Funded by the Wellcome Trust.