Professor of Paediatric Haematology
- Honorary Consultant Paediatric Haematologist
Irene Roberts has been Professor of Paediatric Haematology in the Department of Paediatrics since October 2013. She was previously Professor of Paediatric Haematology at Imperial College London. She is also a Group Leader in the MRC Weatherall Institute of Molecular Medicine where she is based in the MRC Molecular Haematology Unit. She has a longstanding interest in the impact of trisomy 21 on haematopoiesis and her group studies how the biological and molecular properties of fetal stem and progenitor cells provide the permissive cellular context for leukaemia in early childhood.
GATA1-mutant clones are frequent and often unsuspected in babies with Down syndrome: identification of a population at risk of leukemia.
Roberts I. et al, (2013), Blood, 122, 3908 - 3917
Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21.
Roy A. et al, (2012), Proc Natl Acad Sci U S A, 109, 17579 - 17584