Our research

The Department of Paediatrics is a vibrant and inclusive community at the forefront of child health research and clinical care. Our academics and clinicians work side by side to translate world-leading scientific discoveries into real benefits for children and families locally, nationally, and globally. From pioneering clinical trials to cutting-edge laboratory science, our work spans the full spectrum of paediatric and adolescent health including vaccinology, immunology, cancer, genetics, cardiology and rare disease.

Discover our research groups and centres on this webpage, and learn more about our life-changing work.

Founded in 2015, we are investigating the link between human fetal haematopoiesis and the origin and biology of childhood leukaemia. In particular, we are interested in the pathogenesis of infant leukaemia, which is a refractory disease that invariably originates in utero.

Childhood Leukaemia Research Group

Innovative research to improve therapies and outcomes for childhood leukaemia.

Visit the Childhood Leukaemia Group

Developmental Immunology Research Group

Investigating immune system development to understand and prevent childhood disorders.

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The research undertaken in the Draper group focuses on the development of novel and improved approaches to blood-stage malaria vaccine design, as well as aiming to better understand molecular mechanisms of vaccine-induced immunity to blood-stage malaria infection.

Click on the link above to learn more about their research and how to get involved.

Draper Lab | Malaria Vaccines & Immunology

Malaria vaccine research to understand blood-stage infection and improve prevention strategies.

Visit the Draper Lab

The work of this group is focused on prevention of cardiometabolic disease in the young. More people die from such disease worldwide than from any other cause. The majority of these deaths are due to coronary heart disease (CHD) and stroke, potentially preventable conditions.

Early Prevention of Cardiometabolic Disease

Early-life cardiometabolic research to help prevent heart disease and improve lifelong health.

Visit Early Prevention of Cardiometabolic Disease

F1000 | Brain Development in Infancy

Studying brain growth, health and development during the first 1,000 days of life.

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We aim to discover the developmentally-regulated, molecular and biological properties of fetal haematopoietic stem and progenitor cells (HSPC) that provide the permissive cellular context for leukaemia and anemia in early childhood and to investigate the mechanisms which drive these changes.

Fetal & Neonatal Haematology Group

Transforming the understanding and care of paediatric blood diseases.

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HIV Research Group

Improving HIV prevention, treatment and long-term outcomes for children and families.

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IDRM

Bridging developmental biology and regenerative medicine to inform novel treatments for disease.

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Scientists working in an MRC CoRE laboratory.

MRC CoRE in Therapeutic Genomics

Translating genetic insights into therapies for rare and complex disorders.

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Oxford Vaccine Group

Leading global research to develop and evaluate life-saving vaccines.

Visit the Oxford Vaccine Group

Paediatric Neuroimaging

Advanced imaging to understand brain development and neurological disorders in children.

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Rinaldi Lab | Molecular Neuroscience

Bridging molecular neuroscience and therapy discovery for rare neurological conditions.

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Specialised Translational Research Oxford Neuromuscular Group (STRONG)

Leading neuromuscular research that drives better clinical trials, early detection and personalised care.

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Wood Lab | Neuromuscular Science

Bringing biomedical innovation to neuromuscular disease research for the benefit of child health.

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