Anna Prażmo
MD, MBiol
DPhil Student
Understanding the mechanisms by which molecular and phenotypic heterogeneity of MLL-rearranged infant ALL affects clinical outcome.
Contact information
Websites
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SAIL study
SAIL study website at Oxford Cancer
Colleges
Research groups
RESEARCH FOCUS
I joined the Roy Lab in October 2024 as a clinical DPhil in Cancer Science student under the supervision of Professor Andi Roy. My project is a part of Scientific Advances in Infant Leukaemia (SAIL), which aims to deliver a national clinical study that will provide unique insights into optimal treatment pathways for infant acute lymphoblastic leukaemia. We work to create a secure central database held at Oxford to capture demographic, diagnostic, molecular and clinical outcome data from sources such as NHS standard of care laboratory tests, multiomic analysis at the WIMM, as well as information gathered directly from parents. Another aim is a detailed characterisation of each patient's leukaemia to better understand disease biology and response to treatment, which can lead to better stratification and personalised medicine approach.
BACKGROUND
Before returning to Hertford College for the DPhil, I obtained a medical degree in Poland, and an integrated Master in Biology at Oxford, with a first-class thesis on the epidemiology of invasive meningococal disease. In 2024 I completed my foundation medical training, including an elective in paediatric haematooncology, which has been my long-standing interest.