Patricia Gonzalez Dias Carvalho
Postdoctoral Research Associate In Computational Biology
Patricia holds a Master’s Degree in Cellular and Molecular Biology from Instituto Oswaldo Cruz (Fiocruz, Brazil) followed by PhD in Physiopathology and Toxicology at the University of Sao Paulo.
In her master’s degree she studied the immune response induced by different adjuvants and its application in the development of subunit vaccines in the pre-clinical phase. While in her PhD she started to work as a Computational Biologist. She has been working since then on integrative analyses of immunomic, transcriptomic and reactogenic data using systems biology and machine learning approaches to decipher the immune and molecular signatures of the human response elicited by different vaccines and infections.
She joined OVG in 2022 and has been working mainly with respiratory infections disease using data from Experimental Human Challenge Platform. Her main focus at the moment is to identify immune correlates of protection to Pneumococcal infection.
Recent publications
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Inflammation of the nasal mucosa is associated with susceptibility to experimental pneumococcal challenge in older adults.
Urban BC. et al, (2024), Mucosal Immunol, 17, 973 - 989
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Systems Immunology Approaches to Understanding Immune Responses in Acute Infection of Yellow Fever Patients
Gonçalves ANA. et al, (2024)
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Global blood miRNA profiling unravels early signatures of immunogenicity of Ebola vaccine rVSVΔG-ZEBOV-GP.
Vianello E. et al, (2023), iScience, 26
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Cellular and Transcriptional Signature of the Nasal Mucosa is Associated with Susceptibility to Pneumococcal Carriage in Older Adults
Urban BC. et al, (2023)
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Baseline gene signatures of reactogenicity to Ebola vaccination: a machine learning approach across multiple cohorts.
Gonzalez Dias Carvalho PC. et al, (2023), Front Immunol, 14