Parvinder Aley

• Nicotinic acid adenine dinucleotide phosphate (NAADP) is a second messenger in muscarinic receptor-induced contraction of guinea pig trachea.

  Aley PK. et al, (2013), J Biol Chem, 288, 10986 - 10993

• A safe lithium mimetic for bipolar disorder.

  Singh N. et al, (2013), Nat Commun, 4

• ß-Adrenergic receptor signaling increases NAADP and cADPR levels in the heart

  Lewis AM. et al, (2012), Biochemical and Biophysical Research Communications, 427, 326 - 329

• β-Adrenergic receptor signaling increases NAADP and cADPR levels in the heart.

  Lewis AM. et al, (2012), Biochem Biophys Res Commun, 427, 326 - 329

• Erratum: Nicotinic acid adenine dinucleotide phosphate regulates skeletal muscle differentiation via action at two-pore channels (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, (19927-19932) DOI: 10.1073/pnas.1007381107)

  Aley PK. et al, (2011), Proceedings of the National Academy of Sciences of the United States of America, 108

• Acidic NAADP-sensitive calcium stores in the endothelium: agonist-specific recruitment and role in regulating blood pressure.

  Brailoiu GC. et al, (2010), J Biol Chem, 285, 37133 - 37137

• Nicotinic acid adenine dinucleotide phosphate regulates skeletal muscle differentiation via action at two-pore channels.

  Aley PK. et al, (2010), Proc Natl Acad Sci U S A, 107, 19927 - 19932

• A functional role for nicotinic acid adenine dinucleotide phosphate in oxytocin-mediated contraction of uterine smooth muscle from rat.

  Aley PK. et al, (2010), J Pharmacol Exp Ther, 333, 726 - 735

• Fluorescent copper(II) bis(thiosemicarbazonates): synthesis, structures, electron paramagnetic resonance, radiolabeling, in vitro cytotoxicity and confocal fluorescence microscopy studies.

  Pascu SI. et al, (2010), Chem Asian J, 5, 506 - 519

• Analogues of the nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist Ned-19 indicate two binding sites on the NAADP receptor.

  Rosen D. et al, (2009), J Biol Chem, 284, 34930 - 34934

• Recruitment of NAADP-sensitive acidic Ca2+ stores by glutamate.

  Pandey V. et al, (2009), Biochem J, 422, 503 - 512

• Hypoxic modulation of ca(2+) signaling in human venous and arterial endothelial cells.

  Aley PK. et al, (2009), J Membr Biol, 227, 151 - 158

• Hypoxic remodelling of Ca(2+) signalling in proliferating human arterial smooth muscle.

  Aley PK. et al, (2008), Mol Cell Biochem, 318, 101 - 108

• Cell-permeant NAADP: a novel chemical tool enabling the study of Ca2+ signalling in intact cells.

  Parkesh R. et al, (2008), Cell Calcium, 43, 531 - 538

• Simvastatin inhibits TNFalpha-induced invasion of human cardiac myofibroblasts via both MMP-9-dependent and -independent mechanisms.

  Turner NA. et al, (2007), J Mol Cell Cardiol, 43, 168 - 176

• Hypoxic regulation of Ca2+ signalling in astrocytes and endothelial cells.

  Peers C. et al, (2006), Advances in experimental medicine and biology., 580

• Hypoxic regulation of Ca2+ signalling in astrocytes and endothelial cells.

  Peers C. et al, (2006), Adv Exp Med Biol, 580, 185 - 190

• Hypoxia stimulates Ca2+ release from intracellular stores in astrocytes via cyclic ADP ribose-mediated activation of ryanodine receptors.

  Aley PK. et al, (2006), Cell Calcium, 39, 95 - 100

• Hypoxic modulation of Ca2+ signaling in human venous endothelial cells. Multiple roles for reactive oxygen species.

  Aley PK. et al, (2005), J Biol Chem, 280, 13349 - 13354

Recent Publications

• Nicotinic acid adenine dinucleotide phosphate (NAADP) is a second messenger in muscarinic receptor-induced contraction of guinea pig trachea.

  Aley PK. et al, (2013), J Biol Chem, 288, 10986 - 10993

• A safe lithium mimetic for bipolar disorder.

  Singh N. et al, (2013), Nat Commun, 4

• ß-Adrenergic receptor signaling increases NAADP and cADPR levels in the heart

  Lewis AM. et al, (2012), Biochemical and Biophysical Research Communications, 427, 326 - 329

• β-Adrenergic receptor signaling increases NAADP and cADPR levels in the heart.

  Lewis AM. et al, (2012), Biochem Biophys Res Commun, 427, 326 - 329

• Erratum: Nicotinic acid adenine dinucleotide phosphate regulates skeletal muscle differentiation via action at two-pore channels (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, (19927-19932) DOI: 10.1073/pnas.1007381107)

  Aley PK. et al, (2011), Proceedings of the National Academy of Sciences of the United States of America, 108