Paediatric Academic Clinical Fellow
My project is on HIV, looking at virus evolution in infants and in mother-to-child transmission. I am looking to see if there is any evidence of a functional immune response in early infancy to drive virus evolution and if there are any specific viral characteristics that favour mother-to-child transmission.
The advantages of the ACF post are the dedicated research time allocated and the support provided as part of the programme (from OUCAGS and through teaching such as the diploma in health research). The paediatric ACF programme allows me to have dedicated research time without extending my clinical training. This does mean significantly less time for clinical work and for completing assessments to get signed off for ARCP.
There is a wealth of world-renowned research in infectious diseases and global health carried out in Oxford, so it’s a great choice for anyone with an interest in these areas. Oxford has a stimulating academic environment, which you have the opportunity to access when becoming an ACF. Oxford was also one of a few deaneries that accepted paediatric ACFs at ST2 level.
The ACF programme has confirmed my plan to pursue a career in academic medicine and I will apply for PhD funding with a view to starting at the end of ST5.
Repeat controlled human malaria infection of healthy UK adults with blood-stage Plasmodium falciparum: safety and parasite growth dynamics
Salkeld J. et al, (2022)
Impact of a blood-stage vaccine on Plasmodium vivax malaria.
Hou MM. et al, (2022)
Repeat controlled human malaria infection of healthy UK adults with blood-stage Plasmodium falciparum: Safety and parasite growth dynamics.
Salkeld J. et al, (2022), Front Immunol, 13
Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial.
Ramasamy MN. et al, (2021), Lancet, 396, 1979 - 1993
Controlled human malaria infection with a clone of Plasmodium vivax with high-quality genome assembly.
Minassian AM. et al, (2021), JCI Insight, 6