Postdoctoral Research Scientist
I am a post-doctoral researcher in Professor Matthew Wood’s laboratory and I am particularly interested in translating the therapeutic potential of exosomes towards the clinic. More specifically, I have been developing engineered exosomes as therapeutics for Duchenne Muscular Dystrophy.
Gene therapies for polyglutamine diseases
Matos C. et al, (2020), Polyglutamine Disorders
Extracellular microRNAs exhibit sequence-dependent stability and cellular release kinetics.
Coenen-Stass AML. et al, (2019), RNA Biol, 16, 696 - 706
Intravenous administration of brain-targeted stable nucleic acid lipid particles alleviates Machado-Joseph disease neurological phenotype
Conceição M. et al, (2016), Biomaterials, 82, 124 - 137
Safety profile of the intravenous administration of brain-targeted stable nucleic acid lipid particles
Conceição M. et al, (2016), Data in Brief, 6, 700 - 705
Overexpression of Mutant Ataxin-3 in Mouse Cerebellum Induces Ataxia and Cerebellar Neuropathology
Nóbrega C. et al, (2013), The Cerebellum, 12, 441 - 455