Senior Research Scientist
Luke is currently a PhD student studying neonatal pain in Prof Rebeccah Slater’s lab. He is interested in the unique challenges faced during infant MRI, such as differences in brain structure and physiology and large degree of subject motion compared to healthy adults. He has focused on optimising preprocessing and analysis methods tailored to this age group. Luke is also interested in understanding the sources of individual variability in response to noxious stimuli, with a focus on spontaneous brain activity. Specifically, he is interested in looking at how resting-state fMRI activity relates to patterns of noxious-evoked brain activity and pain-related behaviour in newborn infants.
This research could increase our understanding of individual infant's sensitivity to pain and how this might change over time and with experience. An fMRI-derived subject-specific metric of noxious evoked activity may also be an invaluable addition in the repertoire of metrics used in infant pain research.
Luke is currently a member of St Cross College, completed his MSc in Neuroscience in 2014 at University of Oxford and his BSc in Neuroscience in 2013 at University College Cork.
Multicentre, randomised controlled trial to investigate the effects of parental touch on relieving acute procedural pain in neonates (Petal)
Cobo MM. et al, (2022), BMJ Open, 12
Early life inflammation is associated with spinal cord excitability and nociceptive sensitivity in human infants.
Cobo MM. et al, (2022), Nat Commun, 13
Concurrent mapping of brain ontogeny and phylogeny within a common connectivity space
Warrington S. et al, (2022)
The Developing Human Connectome Project Neonatal Data Release.
Edwards AD. et al, (2022), Front Neurosci, 16
Premature Infants Display Discriminable Behavioral, Physiological, and Brain Responses to Noxious and Nonnoxious Stimuli.
van der Vaart M. et al, (2021), Cereb Cortex