Research groups
Jesús Reiné
Postdoctoral Research Associate and CL-3 Deputy Officer
BSc, MSc, MEd, CL-3d, DLSO, PhD
Jesús Reiné obtained his BSc in Biology with Hons from University of Granada, Spain in 2002. In 2004, he was awarded the prestigious CAM PhD fellowship, and subsequently he obtained his PhD in Immunology in the School of Medicine from Universidad Complutense de Madrid, Spain in 2011. Afterwards, he worked in a flow cytometry SME as a Lab Manager, where he was proactively involved in flow cytometry product development (single and combined labelled antibodies categorised as RUO, ASR and/or IVD), and in the design of innovative multiparametric flow cytometry panels, their standardisation and harmonisation with different methodological flow cytometry approaches and instruments.
From 2014 to 2022, he was part of the Liverpool School of Tropical Medicine in Daniela Ferreira’s lab as a post-doctoral research associate and flow cytometry manager. He played a proactive and executive role in the development of innovative and challenging flow cytometry procedures successfully (conventional and spectral) for CL-2 (human challenge studies, clinical trials) and CL-3 (Tropical diseases, SARS-CoV-2) with complex multiparametric panels using non-conventional samples.
Since 2022, he joined the University of Oxford in Daniela Ferreira’s lab team within the Paediatrics Department – Medical Science Division under the umbrella of the Oxford Vaccine Group as a senior postdoc and CL-3 Deputy officer, where is working in the development of novel vaccines using his flow cytometry expertise and associated innovative immunological methods.
Research
- Development of innovative immunological methods and biomarkers in CL-2 and CL-3 scenario.
- Mucosal immune responses against to respiratory pathogens
- Host and pathogen interactions during respiratory bacterial and viral co-infections
Teaching
Since 2014, I am teaching flow cytometry methods, laser safety and biosafety procedures in CL-2 and CL-3 scenario to master students, research assistants and researchers. Due to my flow cytometry expertise, I am also part of the invited lecturers to the Immunology course of the Masters in Tropical Disease Biology at LSTM and the Immunology Master at the Universidad Complutense de Madrid. At Oxford, I am also the coordinator and main responsible of the SuperUsers (trainers of flow cytometry) and the Departmental Laser Safety Officer (DLSO). Our flow cytometry facility is composed by 11 instruments and 9 trainers at the IDRM promoting the standardisation of procedures, laser safety training, and the harmonisation between different flow cytometry instruments.
Recent publications
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Tissue-specific modulation of CRISPR activity by miRNA-sensing guide RNAs.
Garcia-Guerra A. et al, (2025), Nucleic Acids Res, 53
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Inflammation of the nasal mucosa is associated with susceptibility to experimental pneumococcal challenge in older adults.
Urban BC. et al, (2024), Mucosal Immunol, 17, 973 - 989
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RSV and rhinovirus increase pneumococcal carriage acquisition and density, whereas nasal inflammation is associated with bacterial shedding.
Mitsi E. et al, (2024), Cell Host Microbe
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Tetanus-diphtheria vaccine can prime SARS-CoV-2 cross-reactive T cells
Fernandez SA. et al, (2024), Frontiers in Immunology, 15
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Biomarker Predictors of Clinical Efficacy of the Anti-IgE Biologic, Omalizumab, in Severe Asthma in Adults: Results of the SoMOSA Study.
Djukanović R. et al, (2024), Am J Respir Crit Care Med