Georg Holländer

MA (Oxon), MD, FMedSci, FRCPCH, FMH Paediatrics (CH)

Hoffmann and Action Medical Research Professor of Developmental Medicine

Head of Department

Understanding the development and function of the immune system in health and disease

Prof. Georg A Holländer was trained in both Paediatrics and Experimental Immunology in Switzerland and the U.S. He held academic positions at Harvard Medical School, Boston, U.S. and the University of Basel, Switzerland, before he joined the University of Oxford, UK (2010). He is interested in the development and function of the immune system in health and disease. His particular scientific focus concerns the molecular and cellular control of thymus development and function.

Recent publications

Comprehensively Profiling the Chromatin Architecture of Tissue Restricted Antigen Expression in Thymic Epithelial Cells Over Development
Journal article

HANDEL AE. et al, (2018), Frontiers in immunology, 9
Retinoic Acid Signaling in Thymic Epithelial Cells Regulates Thymopoiesis.
Journal article

Wendland K. et al, (2018), J Immunol
Despite high levels of expression in thymic epithelial cells, miR-181a1 and miR-181b1 are not required for thymic development.
Journal article

Stefanski HE. et al, (2018), PLoS One, 13
Cadherin 17 mutation associated with leaky severe combined immune deficiency is corrected by HSCT.
Journal article

Smith AR. et al, (2017), Blood advances, 1, 2083 - 2087
T cell progenitor therapy-facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction.
Journal article

Smith MJ. et al, (2017), JCI insight, 2

More publications