Accelerated epigenetic aging in newborns with Down syndrome
Journal article
Xu K. et al, (2022), Aging Cell
Epigenome-Wide Association Study of Acute Lymphoblastic Leukemia in Children with Down Syndrome.
Journal article
Li S. et al, (2022), Blood Adv
CD34+CD19-CD22+ B-cell progenitors might underlie phenotypic escape in patients treated with CD19-directed therapies.
Journal article
Bueno C. et al, (2022), Blood
Functional impairment of erythropoiesis in Congenital Dyserythropoietic Anaemia type I arises at the progenitor level.
Journal article
Scott C. et al, (2022), Br J Haematol
Increasing Complexity of Molecular Landscapes in Human Hematopoietic Stem and Progenitor Cells during Development and Aging.
Journal article
Watt SM. et al, (2022), Int J Mol Sci, 23
Systems medicine dissection of chr1q-amp reveals a novel PBX1-FOXM1 axis for targeted therapy in multiple myeloma.
Journal article
Trasanidis N. et al, (2022), Blood
A human fetal liver-derived infant MLL-AF4 acute lymphoblastic leukemia model reveals a distinct fetal gene expression program.
Journal article
Rice S. et al, (2021), Nat Commun, 12
Blood and immune development in human fetal bone marrow and Down syndrome.
Journal article
Jardine L. et al, (2021), Nature
Chromatin-based, in cis and in trans regulatory rewiring underpins distinct oncogenic transcriptomes in multiple myeloma.
Journal article
Alvarez-Benayas J. et al, (2021), Nat Commun, 12
Transitions in lineage specification and gene regulatory networks in hematopoietic stem/progenitor cells over human development.
Journal article
Roy A. et al, (2021), Cell Rep, 36
Single-cell profiling of human bone marrow progenitors reveals mechanisms of failing erythropoiesis in Diamond-Blackfan anemia.
Journal article
Iskander D. et al, (2021), Sci Transl Med, 13
Towards sustained human platelet production for therapeutic use
Journal article
Watt SM. and Roberts I., (2021), Annals of Blood, 6
Sowing the seeds of leukemia before birth.
Journal article
Roberts I. and Vyas P., (2021), Science, 373, 155 - 156
The EHA Research Roadmap: Platelet Disorders.
Journal article
Balduini C. et al, (2021), Hemasphere, 5
A KMT2A-AFF1 gene regulatory network highlights the role of core transcription factors and reveals the regulatory logic of key downstream target genes.
Journal article
Harman JR. et al, (2021), Genome Res
Developmental stage- and site-specific transitions in lineage specification and gene regulatory networks in human hematopoietic stem and progenitor cells
Journal article
ROY A. et al, (2021), bioRxiv
Oncogenic Gata1 causes stage-specific megakaryocyte differentiation delay.
Journal article
Juban G. et al, (2021), Haematologica, 106, 1106 - 1119
The innate sensor ZBP1-IRF3 axis regulates cell proliferation in multiple myeloma.
Journal article
Ponnusamy K. et al, (2021), Haematologica
The genome-wide impact of trisomy 21 on DNA methylation and its implications for hematopoiesis.
Journal article
Muskens IS. et al, (2021), Nat Commun, 12
Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia.
Journal article
Louka E. et al, (2021), J Exp Med, 218