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Publications

Safety of a controlled human infection model of tuberculosis with aerosolised, live-attenuated Mycobacterium bovis BCG versus intradermal BCG in BCG-naive adults in the UK: a dose-escalation, randomised, controlled, phase 1 trial

Journal article

Satti I. et al, (2024), The Lancet Infectious Diseases

Deficiency of factor-inhibiting HIF creates a tumor-promoting immune microenvironment.

Journal article

Ma J. et al, (2024), Proc Natl Acad Sci U S A, 121

Revaccination with BCG: does it work?

Journal article

McShane H., (2024), Lancet Infect Dis

Development and application of the direct mycobacterial growth inhibition assay (MGIA): a systematic review

Journal article

MCSHANE H. et al, (2024), Frontiers in Immunology

Optimising the vaccine strategy of BCG, ChAdOx1 85A, and MVA85A for tuberculosis control.

Journal article

Wajja A. et al, (2024), Lancet Infect Dis

Exploring the ethics of tuberculosis human challenge models.

Journal article

Rohrig A. et al, (2023), J Med Ethics

Safety and immunogenicity of ChAdOx1 85A prime followed by MVA85A boost compared with BCG revaccination among Ugandan adolescents who received BCG at birth: a randomised, open-label trial.

Journal article

Wajja A. et al, (2023), Lancet Infect Dis

Adopting human factors in early phase and experimental medicine research: A nested pilot study observing controlled human infection with SARS-CoV-2.

Journal article

Higham HE. et al, (2023), Br J Clin Pharmacol

Improving TB vaccine trial efficiency: A tough nut to crack.

Journal article

Mcshane H., (2023), J Infect Dis

Adopting human factors in early phase and experimental medicine research: A nested pilot study observing controlled human infection with SARS-CoV-2

Preprint

Higham H. et al, (2023)

A five-antigen Esx-5a fusion delivered as a prime-boost regimen protects against M.tb challenge.

Journal article

Stylianou E. et al, (2023), Front Immunol, 14

BCG: Past, Present and Future Direction

Chapter

Morrison H. and McShane H., (2023), Vaccines for Neglected Pathogens: Strategies, Achievements and Challenges: Focus on Leprosy, Leishmaniasis, Melioidosis and Tuberculosis, 171 - 195

Controlled human infection models in COVID-19 and tuberculosis: current progress and future challenges.

Journal article

Morrison H. et al, (2023), Front Immunol, 14

Healthy volunteer symptom profile following research bronchoscopy

Conference paper

Morrison H. et al, (2023), EUROPEAN RESPIRATORY JOURNAL, 62

Practical considerations for a TB controlled human infection model (TB-CHIM); the case for TB-CHIM in Africa, a systematic review of the literature and report of 2 workshop discussions in UK and Malawi.

Journal article

Gordon SB. et al, (2023), Wellcome Open Res, 8

The VALIDATE Network: Accelerating Vaccine Development for Tuberculosis, Leishmaniasis, Melioidosis and Leprosy

Chapter

Vermaak S. et al, (2023), Vaccines for Neglected Pathogens: Strategies, Achievements and Challenges: Focus on Leprosy, Leishmaniasis, Melioidosis and Tuberculosis, 11 - 25

Inflammation and immune activation are associated with risk of Mycobacterium tuberculosis infection in BCG-vaccinated infants.

Journal article

Satti I. et al, (2022), Nat Commun, 13

Functional in-vitro evaluation of the non-specific effects of BCG vaccination in a randomised controlled clinical study.

Journal article

Wilkie M. et al, (2022), Sci Rep, 12

Tuberculosis vaccines in the era of Covid-19 - what is taking us so long?

Journal article

Dockrell HM. and McShane H., (2022), EBioMedicine, 79

Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults.

Journal article

Killingley B. et al, (2022), Nat Med

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