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Publications

LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice.

Prakasam R. et al, (2023), Nat Commun, 14

An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides.

Baker YR. et al, (2022), Nat Commun, 13

AR cooperates with SMAD4 to maintain skeletal muscle homeostasis.

Forouhan M. et al, (2022), Acta Neuropathol, 143, 713 - 731

Oligonucleotide analogues with locked-amide linkages have therapeutic potential

Baker Y. et al, (2022)

Author Correction: GAPDH controls extracellular vesicle biogenesis and enhances the therapeutic potential of EV mediated siRNA delivery to the brain.

Dar GH. et al, (2021), Nat Commun, 12

GAPDH controls extracellular vesicle biogenesis and enhances the therapeutic potential of EV mediated siRNA delivery to the brain.

Dar GH. et al, (2021), Nat Commun, 12

Dystrophin involvement in peripheral circadian SRF signalling.

Betts CA. et al, (2021), Life Sci Alliance, 4

Gene therapy with AR isoform 2 rescues spinal and bulbar muscular atrophy phenotype by modulating AR transcriptional activity.

Lim WF. et al, (2021), Sci Adv, 7

Variants in ATP6V0A1 cause progressive myoclonus epilepsy and developmental and epileptic encephalopathy.

Bott LC. et al, (2021), Brain Commun, 3

Directing an artificial zinc finger protein to new targets by fusion to a non-DNA-binding domain

Lim WF. et al, (2016), Nucleic Acids Res, 44, 3118 - 3130

Differential regulation of the α-globin locus by Krüppel-like Factor 3 in erythroid and non-erythroid cells.

Funnell APW. et al, (2014), BMC Mol Biol, 15

Regions outside the DNA-binding domain are critical for proper in vivo specificity of an archetypal zinc finger transcription factor

Burdach J. et al, (2014), Nucleic Acids Res, 42, 276 - 289

Loss of Kruppel-like factor 3 (KLF3/BKLF) leads to upregulation of the insulin-sensitizing factor adipolin (FAM132A/CTRP12/C1qdc2)

Bell-Anderson KS. et al, (2013), Diabetes, 62, 2728 - 2737

Include forthcoming?