Elevated reactive oxygen species can drive the alternative lengthening of telomeres pathway in ATRX-null cancers.
Goncalves T. et al, (2025), Nucleic Acids Res, 53
Phosphorylation of 'SDT-like' motifs in ATRX mediates its interaction with the MRN complex and is important for ALT pathway suppression.
Goncalves T. et al, (2024), Open Biol, 14
Hypoxia-induced transcriptional stress is mediated by ROS-induced R-loops.
Ma TS. et al, (2023), Nucleic Acids Res
Induction of the alternative lengthening of telomeres pathway by trapping of proteins on DNA.
Rose AM. et al, (2023), Nucleic Acids Res
Risk and Lag-time for Development of Lacrimal Gland Carcinoma Expleomorphic Adenoma: Observations and Conjectural Study.
Rose GE. et al, (2022), Ophthalmic Plast Reconstr Surg
A remarkable case of HbH disease illustrates the relative contributions of the α-globin enhancers to gene expression.
Badat M. et al, (2021), Blood, 137, 572 - 575
Recapitulation of erythropoiesis in congenital dyserythropoietic anaemia type I (CDA-I) identifies defects in differentiation and nucleolar abnormalities.
Scott C. et al, (2020), Haematologica, Online ahead of print
Anti-neutrophil cytoplasmic antibody-positive vasculitis secondary to therapeutic levamisole.
Rose AM., (2020), Rheumatology (Oxford)
Detection of mutations in SF3B1, EIF1AX and GNAQ in primary orbital melanoma by candidate gene analysis.
Rose AM. et al, (2018), BMC Cancer, 18
Cancer and the junkyard chromosome: how repeat DNA sequence on chromosome 19 influences risk of malignant disease.
Rose AM., (2018), Oncotarget, 9, 31942 - 31944
Hb Penang [β78(EF2)Leu→Pro, HBB: c.236T>C]: a Novel β-Globin Variant.
Hsu CH-W. et al, (2018), Hemoglobin, 42, 199 - 202
Multiple primary malignancies and prolonged survival in a patient with widespread metastatic cutaneous melanoma.
Rose AM. et al, (2018), Melanoma Res, 28, 163 - 166
Presentation, Treatment, and Prognosis of Secondary Melanoma within the Orbit.
Rose AM. et al, (2017), Front Oncol, 7
Primary Orbital Melanoma: Presentation, Treatment, and Long-term Outcomes for 13 Patients.
Rose AM. et al, (2017), Front Oncol, 7
Variant haploinsufficiency and phenotypic non-penetrance in PRPF31-associated retinitis pigmentosa.
Rose AM. and Bhattacharya SS., (2016), Clinical genetics, 90, 118 - 126
Transcriptional regulation of PRPF31 gene expression by MSR1 repeat elements causes incomplete penetrance in retinitis pigmentosa.
Rose AM. et al, (2016), Scientific reports, 6
Diverse clinical phenotypes associated with a nonsense mutation in FAM161A.
Rose AM. et al, (2015), Eye (London, England), 29, 1226 - 1232
Late presentation to hospital services necessitates greater community-based care for malnourished children.
Rose AM., (2015), Journal of tropical pediatrics, 61, 61 - 64