Enhancer heterogeneity in acute lymphoblastic leukemia drives differential gene expression in patients.
Smith A. et al, (2025), Blood
PROM1/CD133 MARKS A PROLIFERATIVE STEM CELL LIKE POPULATION OF BLASTS IN KMT2A REARRANGED INFANT ALL.
Cross JW. et al, (2025), Blood Adv
Backtracking to the future: unraveling the origins of childhood leukemia.
de Smith AJ. et al, (2024), Leukemia, 38, 416 - 419
Aberrant stem cell and developmental programs in pediatric leukemia.
Ling RE. et al, (2024), Front Cell Dev Biol, 12
A human genome editing-based MLL::AF4 B-cell ALL model recapitulates key cellular and molecular leukemogenic features.
Bueno C. et al, (2023), Blood
MLL-AF4 cooperates with PAF1 and FACT to drive high-density enhancer interactions in leukemia.
Crump NT. et al, (2023), Nat Commun, 14
Direct correction of haemoglobin E β-thalassaemia using base editors.
Badat M. et al, (2023), Nat Commun, 14
A SINGLE-CELL PROTEIN-TRANSCRIPTOME ATLAS OF HAEMATOPOIESIS ACROSS THE HUMAN LIFESPAN
Londono MQ. et al, (2023), EXPERIMENTAL HEMATOLOGY, 124, S129 - S129
DEVELOPMENTAL ORIGINS OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA
Roy A., (2023), EXPERIMENTAL HEMATOLOGY, 124, S26 - S26
Investigating the roles of fetal-specific genes in hematopoiesis
Welsh A. et al, (2023), JOURNAL OF IMMUNOLOGY, 210
PROM1/CD133 expression identifies highly proliferative MLL-AF4+blasts and correlates with a stem-like gene signature
Cross J. et al, (2023), KLINISCHE PADIATRIE, 235, 193 - 193
Human bone marrow organoids for disease modelling, discovery and validation of therapeutic targets in hematological malignancies.
Khan AO. et al, (2022), Cancer Discov
In utero origin of myelofibrosis presenting in adult monozygotic twins.
Sousos N. et al, (2022), Nat Med, 28, 1207 - 1211
Epigenome-Wide Association Study of Acute Lymphoblastic Leukemia in Children with Down Syndrome.
Li S. et al, (2022), Blood Adv