Protocol 15PRT/5747: A blinded randomised placebo-controlled trial investigating the efficacy of morphine analgesia for procedural pain in infants
Hartley C., Moultrie F., Juszczak E., Adams E., Slater R.
Infant pain has both immediate and long-term negative consequences, yet in clinical practice it is often undertreated. To date, very few pain-relieving drugs have been tested in infants, mainly because of difficulties in assessing response to treatment. Morphine is a potent analgesic that provides effective pain relief in adults, but there is inconclusive evidence for its effectiveness in infants. The purpose of this study is to establish whether oral morphine provides effective analgesia for procedural pain in infants.