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We report on a 30-year-old patient with advanced cerebellar degeneration due to SCA2. He presented with severe myoclonus, which was resistant to conventional therapy and dramatically improved after administration of 12-18 gm/die piracetam. Piracetam may be considered in the treatment of refractory myoclonus in spinocerebellar degenerations.

Original publication

DOI

10.1002/mds.20683

Type

Journal article

Journal

Mov Disord

Publication Date

01/2006

Volume

21

Pages

116 - 118

Keywords

Adult, Ataxia, Ataxins, Dose-Response Relationship, Drug, Gait Ataxia, Humans, Infusions, Intravenous, Male, Myoclonus, Nerve Tissue Proteins, Neurologic Examination, Piracetam, Recurrence, Spinocerebellar Ataxias, Substance Withdrawal Syndrome, Treatment Outcome, Trinucleotide Repeats