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Recent publications

Targeting the 5′ untranslated region of SMN2 as a therapeutic strategy for spinal muscular atrophy

Winkelsas AM. et al, (2021), Molecular Therapy - Nucleic Acids, 23, 731 - 742

The antigenic anatomy of SARS-CoV-2 receptor binding domain

GUPTA S. et al, (2021), Cell

Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials.

Voysey M. et al, (2021), Lancet

Thymus Extracellular Matrix-Derived Scaffolds Support Graft-Resident Thymopoiesis and Long-Term In Vitro Culture of Adult Thymic Epithelial Cells

Asnaghi A. et al, (2021), Advanced Functional Materials

The Origin of B-cells: Human Fetal B Cell Development and Implications for the Pathogenesis of Childhood Acute Lymphoblastic Leukemia

Jackson TR. et al, (2021), Frontiers in Immunology, 12

Procalcitonin, C-reactive protein, neutrophil gelatinase-associated lipocalin, resistin and the APTT waveform for the early diagnosis of serious bacterial infection and prediction of outcome in critically ill children

Nielsen MJ. et al, (2021), PLOS ONE, 16, e0246027 - e0246027

The genome-wide impact of trisomy 21 on DNA methylation and its implications for hematopoiesis.

Muskens IS. et al, (2021), Nat Commun, 12

Changes in epigenetic profiles throughout early childhood and their relationship to the response to pneumococcal vaccination.

Pischedda S. et al, (2021), Clin Epigenetics, 13

Newborn screening of duchenne muscular dystrophy specifically targeting deletions amenable to exon-skipping therapy.

Beckers P. et al, (2021), Sci Rep, 11

Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia.

Louka E. et al, (2021), J Exp Med, 218

High-resolution 3D imaging uncovers organ-specific vascular control of tissue aging.

Chen J. et al, (2021), Sci Adv, 7

Introduction: thymus development and function in health and disease.

Holländer GA., (2021), Semin Immunopathol, 43, 1 - 3

Vi-specific serological correlates of protection for typhoid fever

Jin C. et al, (2021), The Journal of experimental medicine, 218

MAIT cell activation augments adenovirus vector vaccine immunogenicity.

Provine NM. et al, (2021), Science, 371, 521 - 526

Systematic literature review of the economic burden of spinal muscular atrophy and economic evaluations of treatments.

Dangouloff T. et al, (2021), Orphanet J Rare Dis, 16

Molecular correction of Duchenne muscular dystrophy by splice modulation and gene editing.

Hanson B. et al, (2021), RNA Biol, 1 - 15

Expanding the Nude SCID/CID Phenotype Associated with FOXN1 Homozygous, Compound Heterozygous, or Heterozygous Mutations.

Giardino G. et al, (2021), J Clin Immunol

Meningococcal carriage in periods of high and low invasive meningococcal disease incidence in the UK: comparison of UKMenCar1-4 cross-sectional survey results.

MacLennan JM. et al, (2021), Lancet Infect Dis

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK.

Voysey M. et al, (2021), Lancet, 397, 99 - 111

Immunogenicity of the UK group B meningococcal vaccine (4CMenB) schedule against groups B and C meningococcal strains (Sched3): outcomes of a multicentre, open-label, randomised controlled trial.

Davis K. et al, (2021), Lancet Infect Dis

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