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Contact information


miguel.varela@paediatrics.ox.ac.uk


01865 272199

Miguel A. Varela

GROUP LEADER - DRUG DELIVERY

My research focuses on the molecular mechanisms underlying neuromuscular and cardiac diseases, with the aim of identifying therapeutic targets and developing gene-based therapies.

A key challenge in this field is the effective delivery of nucleic acid therapeutics to target tissues such as skeletal and cardiac muscle. To address this, we have developed a suite of delivery technologies, including peptide and antibody-based systems, some of which are now in clinical translation.

Our work integrates RNA biology, delivery science, and therapeutic development, with the ultimate goal of advancing precision medicines for patients with currently untreatable conditions.