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Contact information


miguel.varela@paediatrics.ox.ac.uk


01865 272199

Miguel A. Varela

GROUP LEADER - DRUG DELIVERY

My research sits at the intersection of RNA biology, nucleic acid chemistry, and therapeutic development, with a focus on designing and delivering antisense-based medicines for conditions that currently lack effective treatments.

A key focus of my group is the delivery of nucleic acid therapeutics to tissues that remain difficult to reach, developing peptide- and antibody-conjugated systems that improve tissue uptake and selectivity. Some of this delivery work is progressing towards clinical translation.

Our work integrates chemistry, delivery science, and translational strategy, with the goal of building a platform that can be rapidly adapted across disease indications to deliver precision medicines to patients.