Manman Guo

My work centres on pre-clinical studies related to bacterial vaccine development. Specifically, I am engaged in developing immunoassays to assess immune parameters for establishing a new controlled human challenge model against Clostridium difficile. Additionally, I am involved in studying immune responses to evaluate protection against paratyphoid infection by a combination vaccine.

My passion lies in translational medicine research, a field I have been involved in since 2015, when I worked as a postdoctoral researcher at NDORMS, University of Oxford. During this period, I immersed myself in investigating immune regulations associated with drug development in multiple myeloma, as well as conducting target validation studies of endometriosis.

Prior to that, I obtained my PhD from the MRC Protein Phosphorylation and Ubiquitylation Unit at the University of Dundee. During my doctoral studies, I focused on the phagocytosis of macrophages upon activation, employing a range of methodologies including biochemistry, cell biology, and proteomic approaches.