Jessica Stoodley
DPhil Student / Research Assistant
I am a DPhil student and research assistant with 7 years of experience working on developing treatment for neuromuscular diseases as part of the Wood group. I graduated from the University of Birmingham with a degree in Natural Sciences where my particular focus was medical biochemistry. Upon joining the Wood group, initially worked on developing and testing new therapies for spinal muscular atrophy using antisense oligonucleotide conjugates as part of the SMA team. Since starting my DPhil I have been focusing on developing treatments for the treatment of myotonic dystrophy 1, especially focusing on using antibody-antisense oligonucleotide conjugates targeting the transferrin receptor (TfR1) .
Recent publications
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PRMT inhibitor promotes SMN2 exon 7 inclusion and synergizes with nusinersen to rescue SMA mice.
Kordala AJ. et al, (2023), EMBO Mol Med, 15
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Application of Antisense Conjugates for the Treatment of Myotonic Dystrophy Type 1.
Stoodley J. et al, (2023), Int J Mol Sci, 24
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Peptide-Conjugated PMOs for the Treatment of Myotonic Dystrophy.
Stoodley J. et al, (2023), Methods Mol Biol, 2587, 209 - 237
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Antibody-oligonucleotide conjugate achieves CNS delivery in animal models for spinal muscular atrophy.
Hammond SM. et al, (2022), JCI Insight, 7
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Evaluating Efficacy of Peptide-Delivered Oligonucleotides Using the Severe Taiwanese SMA Mouse Model.
Goli L. et al, (2022), 2383, 491 - 513