Contact information
Jack Saunders
PhD Student
I am a DPhil student supervised by Prof Lambe in the Oxford Vaccine Group. My research focuses on investigating the immune response in both humans and animals against emerging pathogens including Crimean-Congo haemorhagic fever virus (CCHFV) and other closely related bunyaviruses including Nairobi sheep disease virus (NSDV) to aid vaccine design. This works aims to develop and progress novel vaccines against CCHFV and NSDV, and involves exploring new assays to assess humoral immunity and vaccine efficacy.
Before my PhD, I worked at the Jenner Institute as a Research Assistant in the Emerging Pathogens Group on CCHFV and SARS-CoV-2 humoral responses. I completed my undergraduate degree in Biochemistry at the University of Exeter. I then completed my Master's degree in Integrated Immunology at the University of Oxford, involving a research project that explored murine T-cell responses to Chlamydia trachomatis infection.
Recent publications
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Adenoviral vectored vaccination protects against Crimean-Congo Haemorrhagic Fever disease in a lethal challenge model.
Saunders JE. et al, (2023), EBioMedicine, 90
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An attenuated herpesvirus vectored vaccine candidate induces T-cell responses against highly conserved porcine reproductive and respiratory syndrome virus M and NSP5 proteins that are unable to control infection.
de Brito RCF. et al, (2023), Front Immunol, 14
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Development of anti-Crimean-Congo hemorrhagic fever virus Gc and NP-specific ELISA for detection of antibodies in domestic animal sera.
Belij-Rammerstorfer S. et al, (2022), Front Vet Sci, 9
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Reactogenicity and immunogenicity after a late second dose or a third dose of ChAdOx1 nCoV-19 in the UK: a substudy of two randomised controlled trials (COV001 and COV002).
Flaxman A. et al, (2021), Lancet, 398, 981 - 990
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Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials.
Voysey M. et al, (2021), Lancet, 397, 881 - 891