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Typhoid vaccine trial confirms sustained protection for older children

A single dose of typhoid conjugate vaccine (TCV) offers safe, effective protection against typhoid two years after vaccination in all children, and sustained protection for older children at three to five years post immunisation, according to a report by researchers at the Oxford Vaccine Group and icddr,b. But it also shows a decline in protection at the later timepoints among children vaccinated at younger ages.

New campaign launched to encourage vaccine uptake

Oxford Vaccine Group marks 30 years battling ‘deadly six’ diseases with major art installation

A major art installation featuring dramatically upscaled bacteria, viruses and a parasite has been unveiled at Oxford University’s Museum of Natural History to celebrate 30 years of vaccine development by the Oxford Vaccine Group (OVG) which has tackled some of the world’s most deadly diseases.

Launch of new podcast series Trusting the Science

The Oxford Vaccine Group is celebrating 30 years of life-saving vaccine development with the release of a new podcast series of conversations called Trusting the Science. This is the second series of The Oxford Colloquy - discourses hosted by Professor Sir Andrew Pollard who has been Director of the group for over 20 years - and each episode delves into the crucial role that science plays in our understanding of health and immunity.

Athena Swan Gold award

The Department of Paediatrics has been awarded the Athena Swan Gold award for its commitment to advancing gender equality in higher education. Established in 2005 to encourage and recognise commitment to advancing the careers of women in science, technology, engineering, maths and medicine (STEMM) employment, the Charter is now used across the globe to address gender equality and barriers to progression that affect women.

New research identifies autoimmunity against a key anti-inflammatory regulator in inflammatory bowel disease

A ground-breaking study, published by the New England Journal of Medicine, has identified a new disease-inducing mechanism for inflammatory bowel disease (IBD) in which the immune system attacks its own regulatory function.

Oxford scientists launch first-in-human vaccine trial for deadly Marburg virus

Scientists at the University of Oxford have launched a new clinical trial to test a vaccine to protect people against deadly Marburg virus.

New discovery renews hope for thousands with neurodevelopment disorders

A global collaboration led by scientists at the University of Oxford has discovered that genetic variants in a specific gene cause a rare neurodevelopmental disorder (NDD). NDD is a collective term for severe impairments in how the brain functions that impact learning, behaviour, speech, and movement. Most NDDs are thought to be genetic and caused by changes to DNA, however, to date, around 60% of individuals with these conditions do not know the specific DNA change that causes their disorder.

New trial launches for two-in-one vaccine to prevent RSV and hMPV

Scientists at the University of Oxford have launched a phase 1 study to test two investigational mRNA vaccines: one for both respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) and a second for RSV alone in infants aged five to eight months old. The vaccines are being developed by Moderna.

Research shows early life immunity increases HIV cure/remission in male infants

New research published by scientists at the University of Oxford, the University of KwaZulu-Natal and the Africa Health Research Institute in South Africa, and the Ragon Institute of Mass General, MIT and Harvard, USA, shows that male infants are more likely to achieve HIV cure/remission than females.

GOSH Charity co-funds two data-driven projects to advance research into childhood cancers

Great Ormond Street Hospital (GOSH) Charity has joined forces with Cancer Research UK (CRUK) to co-fund two projects that will use data science to advance research into childhood cancers.

New research assesses the function of a major genetic cause of neurodevelopmental disorders

New research, published today, has defined the functional impacts of hundreds of variants in a gene that is a major cause of neurodevelopmental disorders.

Professor Teresa Lambe OBE elected to the Fellowship of the Academy of Medical Sciences

Professor Teresa Lambe OBE, Calleva Head of Immunology at the Oxford Vaccine Group, and Principal Investigator at the Pandemic Sciences Institute, has been elected a Fellow of the Academy of Medical Sciences, one of the most prestigious awards in the field.

Professor Sir Andrew Pollard elected to the Fellowship of the Royal Society

Professor Sir Andrew Pollard, Director of the Oxford Vaccine Group at the Department of Paediatrics, and Ashall Professor of Infection and Immunity has today been elected a Fellow of the Royal Society.

Ground-breaking study reveals how COVID-19 vaccines prevent severe disease

A landmark study by scientists at the University of Oxford, has unveiled crucial insights into the way that COVID-19 vaccines mitigate severe illness in those who have been vaccinated.

How the Information Security Office and the National Cyber Security Centre keeps Oxford's research secure post-pandemic

Oxford University's Information Security Office (InfoSec) invited the NCSC to Oxford to thank them for the work they did that kept Oxford’s vaccine research secure.

Oxford hosts Belgian vaccine experts

Researchers from Oxford Vaccine Group and the Pandemic Sciences Institute welcomed a delegation of vaccine researchers from Belgium to further UK-Belgian collaboration on vaccine development and manufacture.

Advancing a malaria vaccine for better global health outcomes

Professor Sue Ann Costa Clemens CBE, Chair of Global Health at the Department of Paediatrics and Head of Oxford Latam Research Group – a collaboration between Oxford and Brazil, aimed at strengthening our commitment to global health – met with His Excellency Antonio Patriota, Brazilian Ambassador to the UK, to discuss the co-development of a Malaria vaccine and advance public health outcomes in Brazil.

New trial to study how the human immune system adapts to ‘tolerate’ malaria parasites

Scientists at the University of Oxford and the University of Edinburgh have launched a pioneering study that examines how the immune system responds to repeated malaria infections. The BIO-004 study is being run in partnership between the Department of Biochemistry (Draper Lab, based in the Kavli Institute for Nanoscience Discovery), the University of Edinburgh (Spence Lab, Institute of Immunology and Infection Research) and the Oxford Vaccine Group (part of the Department of Paediatrics). BIO-004 will provide a unique insight into how the immune system adapts over the first few malaria infections of life, learning to tolerate malaria parasites and developing natural immunity to severe illness.

Research shows comforting babies eases parental stress in painful procedures

The Neuroimaging Group, at the Department of Paediatrics, in collaboration with Bliss, the charity for babies born premature or sick, has launched a new suite of information resources for parents of neo-nates, designed to make them feel more confident about being involved in the care of their babies.

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