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A new hepatitis C vaccine has shown promising results in an early clinical trial at Oxford University, generating strong and broad immune responses against the virus causing the disease.
New trial to study how the human immune system adapts to ‘tolerate’ malaria parasites
Clinical Trials Research Research Methods Vaccinology
18 March 2024
Scientists at the University of Oxford and the University of Edinburgh have launched a pioneering study that examines how the immune system responds to repeated malaria infections. The BIO-004 study is being run in partnership between the Department of Biochemistry (Draper Lab, based in the Kavli Institute for Nanoscience Discovery), the University of Edinburgh (Spence Lab, Institute of Immunology and Infection Research) and the Oxford Vaccine Group (part of the Department of Paediatrics). BIO-004 will provide a unique insight into how the immune system adapts over the first few malaria infections of life, learning to tolerate malaria parasites and developing natural immunity to severe illness.
Research shows comforting babies eases parental stress in painful procedures
Neuroimaging Parents & Carers Research
8 March 2024
The Neuroimaging Group, at the Department of Paediatrics, in collaboration with Bliss, the charity for babies born premature or sick, has launched a new suite of information resources for parents of neo-nates, designed to make them feel more confident about being involved in the care of their babies.
Novartis Global Scholar Program award for Neuromuscular team
Awards & Appointments Department Neuromuscular Diseases Research
6 March 2024
Many congratulations to Associate Professor Carlo Rinaldi and Senior Postdoctoral Scientist Antonio Garcia-Guerra, who have been awarded the Novartis Global Scholar Program (NGSP) for 2023.
Clinical Lecturer in Paediatrics selected as finalist for the MRC Impact Prize 2023: Early Career Impact
Awards & Appointments Department Public Engagement Research
29 February 2024
Dr Michelle Fernandes, a Clinical Lecturer at the Department of Paediatrics, Research Fellow at the Nuffield Department of Women’s & Reproductive Health, and Associate Fellow at Green Templeton College has been selected as a finalist for the Medical Research Council (MRC) Impact Prize 2023, for her cross-disciplinary research in international early child development.
New animation series to support parents of premature infants
Children's Health Department Neuroimaging Parents & Carers Public Engagement Research
27 February 2024
Professor Caroline Hartley, Principal Investigator, and Dr Marianne van der Vaart Postdoctoral Researcher, in the Paediatric Neuroimaging Group at the Department of Paediatrics, have today launched a series of animations aimed at improving parental understanding of brain development in premature infants, and the effect it has on breathing and apnoeas (the cessation of breathing).
New protein discovery sheds light on complexity of genetic regulation
Department Publication Research
21 February 2024
Scientists at the Department of Paediatrics have discovered a new pathway that the human body uses to silence transposable elements or ‘jumping genes’. Dr. Rebecca Berrens, Principal Investigator in the Transposon Group, has published research into the piRNA pathway, a key process our body uses to keep these transposable elements in check.
Associate Professor Carlo Rinaldi awarded prestigious Clinical Fellowship
Awards & Appointments Department Neuromuscular Diseases Research
16 February 2024
Associate Professor Carlo Rinaldi, a Consultant Neurologist and Clinician Scientist at the Department of Paediatrics, has been awarded the prestigious UKRI MRC Senior Clinical Fellowship for 2024.
Oxford University professors on the record with their contribution to the fight against cancer for this World Cancer Day
Department Haematology Research University
4 February 2024
This World Cancer Day, four Principal Investigators from the University of Oxford, including Andi Roy, Professor of Paediatric Haematology at the Department of Paediatrics, talk candidly about their work and how they’re helping the fight against cancer.
MDUK Oxford Neuromuscular Centre celebrates five year anniversary
Clinical Trials Department Neuromuscular Diseases Research
31 January 2024
The Department of Paediatrics at the University of Oxford is celebrating the five-year anniversary of a partnership with MDUK. Founded in January 2019, the MDUK Oxford Neuromuscular Centre was set up to drive the development of new therapies and treatments and increase the capacity of clinical trials for muscle wasting and weakening conditions in the UK.
First in-human vaccine trial for Nipah virus
Clinical Trials Immunology Research Vaccinology
11 January 2024
The University of Oxford has launched a new clinical trial to test a vaccine against the deadly Nipah virus.
OVG receives £7.8 million in research funding to fight pandemic and epidemic threats
COVID-19 Research Vaccinology
12 December 2023
Oxford Vaccine Group (OVG), which led the rapid clinical development of the Oxford vaccine in COVID-19 in the pandemic, has been awarded a total of £7,788,783 by UK Aid for research into the prevention of five dangerous diseases with epidemic or pandemic potential.
DoP researcher awarded prestigious NIHR professorship
Awards & Appointments COVID-19 Department Research Research Methods
20 November 2023
Daniela Ferreira, Professor of Respiratory Infection and Vaccinology at the University of Oxford’s Department of Paediatrics and the Department of Clinical Sciences at the Liverpool School of Tropical Medicine has been awarded one of six prestigious Research Professorships by the National Institute of Health and Care Research (NIHR).
Oxford welcomes global pandemic experts for focus on 100 Days Mission
COVID-19 Department Informing Policy Research Vaccinology
3 November 2023
Experts linked to the International Pandemic Preparedness Secretariat (IPPS) visited the University of Oxford’s vaccine laboratories this week as part of a two-day gathering on accelerating pandemic preparedness.
CEPI funding announced for development of vaccine prototype
Awards & Appointments COVID-19 Research Vaccinology
2 November 2023
The University of Oxford and the Coalition for Epidemic Preparedness Innovations (CEPI) today announced the launch of a new project to initiate early development of prototype vaccines against the Junín virus, selected as an exemplar of the Arenavirus family which is responsible for multiple deadly haemorrhagic fevers with epidemic and pandemic potential.
Oxford launches new vaccine trial to enhance design of flu & COVID-19 vaccines
COVID-19 Clinical Trials Immunology Public Engagement Recruitment Research Vaccinology
25 October 2023
A pioneering study into human immunity is being launched today by Oxford Vaccine Group at the University of Oxford. The study, called LEGACY03, is being funded by the Medical Research Council part of UK Research and Innovation. By investigating how lymph nodes work, and how they make responses to vaccines in younger and older people, it has the potential to improve vaccine design for different age groups significantly.
The Oxford-Harrington Rare Disease Centre Launches Pioneering Therapeutics Accelerator to Advance Innovative Treatments for Rare Diseases
Children's Health Public Engagement Research University
3 October 2023
The University of Oxford and Harrington Discovery Institute at University Hospitals in Cleveland, Ohio announced the launch of the Oxford-Harrington Rare Disease Centre Therapeutics Accelerator with an official signing event at the University of Oxford. The event was hosted by the Oxford-Harrington Rare Disease Centre (OHC), a partnership established in 2019 between the University of Oxford and Harrington Discovery Institute. Attendance at the signing included leaders from OHC, the University of Oxford, the Harrington family, University Hospitals, and Oxford Science Enterprises.
Future of Chair in Global Health secured with £5 million gift
Awards & Appointments Department Research Teaching University
20 September 2023
The University of Oxford’s commitment to tackling major global health challenges has been strengthened following the endowment of a chair in global health and clinical development. The new permanent post was made possible by a £5 million donation from Brazilian healthcare organisation SAIL for Health.
Anindita Roy appointed Professor of Paediatric Haematology
Awards & Appointments Haematology Research Teaching University
13 September 2023
The Department of Paediatrics at the University of Oxford is delighted to announce that Anindita Roy has been named Professor of Paediatric Haematology at the University of Oxford.
First in-human trials commence for CCHF vaccine
COVID-19 Clinical Trials Research Vaccinology
12 September 2023
A University of Oxford study has administered a new vaccine against tick-borne virus Crimean-Congo haemorrhagic fever (CCHF) to human volunteers for the first time. The clinical trial of the ChAdOx2 CCHF vaccine aims to confirm its safety and understand how individuals develop immunity following vaccination.
University of Oxford partners with CEPI to counter the threat of future pandemics
COVID-19 Research University Vaccinology
31 August 2023
The University of Oxford and the Coalition for Epidemic Preparedness Innovations (CEPI) have entered into a strategic partnership to accelerate the development of safe, effective and globally accessible vaccines to counter the threat of future pandemics.