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Search results (216)

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FOXN1 remodels chromatin access and schedules fitness during thymus ontogeny

Dhalla F. et al, (2026)

Beyond conventional adoptive T-cell therapy.

Cavazzana M. et al, (2025), J Allergy Clin Immunol, 156, 867 - 877

The transcriptional repressor AEBP2 is indispensable for the epigenetic control of mimetic thymic epithelial cell differentiation and central self-tolerance induction

Wu W. et al, (2025)

Distinct type I and II interferon responses direct cortical and medullary thymic epithelial cell development.

Mohammed A. et al, (2025), Sci Immunol, 10

Paracrine FGF21 dynamically modulates mTOR signaling to regulate thymus function across the lifespan.

Wedemeyer SA. et al, (2025), Nat Aging, 5, 588 - 606

A feedback amplifier circuit with Notch and E2A orchestrates T-cell fate and suppresses the innate lymphoid cell lineages during thymic ontogeny.

Miyazaki K. et al, (2025), Genes Dev, 39, 384 - 400

Dominant negative variants in ITPR3 impair T cell Ca2+ dynamics causing combined immunodeficiency.

Blanco E. et al, (2025), J Exp Med, 222

European Society for Immunodeficiencies guidelines for the management of patients with congenital athymia.

Kreins AY. et al, (2024), J Allergy Clin Immunol, 154, 1391 - 1408

AB056. Spatial analysis of T-cell development in type B2 thymoma tumour microenvironment at single-cell resolution

Hanna KS. et al, (2024), Mediastinum, 8, ab056 - ab056

Thymic epithelial organoids mediate T-cell development.

Hübscher T. et al, (2024), Development, 151

Thymus development

Holländer GA. and Barthlott T., (2024), 159 - 177

AB009. Spatial proteomic analysis of the human thymic microenvironment shaping T cell development

Hanna K. et al, (2023), Mediastinum, 7

Structural and non-coding variants increase the diagnostic yield of clinical whole genome sequencing for rare diseases.

Pagnamenta AT. et al, (2023), Genome Med, 15

Let-7 enhances murine anti-tumor CD8 T cell responses by promoting memory and antagonizing terminal differentiation.

Wells AC. et al, (2023), Nat Commun, 14

Combined multidimensional single-cell protein and RNA profiling dissects the cellular and functional heterogeneity of thymic epithelial cells.

Klein F. et al, (2023), Nat Commun, 14

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