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The authors describe an infant presenting at 2 weeks of age with congenital acute lymphoblastic leukemia who had previously received routine bacille Calmette-Guérin (BCG) vaccination at birth. The risk of BCG dissemination in immunocompromised infants is discussed and the use of antimycobacterial prophylaxis in such cases considered.

Type

Journal

J Pediatr Hematol Oncol

Publication Date

02/2004

Volume

26

Pages

112 - 115

Keywords

Antineoplastic Combined Chemotherapy Protocols, BCG Vaccine, Cicatrix, Fatal Outcome, Female, Humans, Immunocompromised Host, Infant, Newborn, Mycobacterium bovis, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Tuberculosis, Vaccination, Virus Activation