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Mammals coexist in an overall symbiotic relationship with a complex array of commensal bacterial flora that colonizes the gastrointestinal tract. These intestinal bacteria interface with cells of the mucosal immune system, including DCs (see the related article beginning on page 693). Here we discuss mechanisms of interaction between intestinal bacteria and DCs and the role of localized gastrointestinal immune responses.

Original publication

DOI

10.1172/JCI200319545

Type

Journal article

Journal

Journal of Clinical Investigation

Publication Date

01/09/2003

Volume

112

Pages

648 - 651