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AstraZeneca has reached an agreement with Europe’s Inclusive Vaccines Alliance (IVA), spearheaded by Germany, France, Italy and the Netherlands, to supply up to 400 million doses of the University of Oxford’s COVID-19 vaccine, with deliveries starting by the end of 2020.

Design, validation, and functional impact of oligonucleotides for multigene silencing in Alzheimer's disease.

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Woffindale C. et al, (2026), Mol Ther Nucleic Acids, 37

Structure-guided design of a PfCyRPA-based vaccine against blood-stage malaria.

Journal article

Alam N. et al, (2026), EMBO Mol Med

Broad lessons from negative trials in rare diseases.

Journal article

Servais L. and Oskoui M., (2026), Lancet Neurol, 25, 215 - 217

Securing the future of immunisation: ESCMID’s vision

Journal article

Ramasamy MN. et al, (2026), CMI Communications, 3, 105167 - 105167

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New clinical trials begin in Burkina Faso

Vaccinations have started at the Institut de Recherche en Sciences de la Santé – Clinical Research Unit of Nanoro (IRSS-URCN), Burkina Faso for two clinical trials to assess the blood-stage malaria vaccine candidates R78C and RH5.1 with Matrix-M (developed by the Draper Lab in the Department of Paediatrics), in combination with the R21/​Matrix-M vaccine, which targets the earlier liver-stage. The trials are sponsored by the University of Oxford (UOXF), UK, with the European Vaccine Initiative (EVI) acting as both a co-funder and collaborator. These exciting studies are expected to provide proof-of-concept for the use of a multi-stage vaccine to extend the protection against malaria and help lead to future efforts to eliminate it by targeting two stages of the parasite’s life-cycle.