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A 13 year old Asian girl presenting with apparent hysterical paralysis and subsequent rapid cycling bipolar mood disorder was found to have biochemical evidence of pseudohypoparathyroidism type II. The mood disorder responded to treatment of the pseudohypoparathyroidism with a vitamin D analogue. Investigation of her parents and siblings showed phenotypes consistent with two distinct types of pseudohypoparathyroidism (type I and type II) in different family members.

Type

Journal article

Journal

Arch Dis Child

Publication Date

02/1994

Volume

70

Pages

99 - 102

Keywords

Adolescent, Adult, Bipolar Disorder, Child, Child, Preschool, Family, Female, Humans, Male, Paralysis, Parathyroid Hormone, Pedigree, Pseudohypoparathyroidism, Psychomotor Disorders, Vitamin D