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Viral RNA is a common activator of antiviral responses. In this review, we dissect the mechanism of viral RNA recognition by the small interfering RNA pathway in Drosophila melanogaster. This antiviral response in fruit flies can help understand general principles of nucleic acid recognition.

More information

DOI

10.1016/j.micinf.2014.09.001

Type

Journal article

Publication Date

01/12/2014

Volume

16

Pages

1013 - 1021

Total pages

8

Keywords

Drosophila melanogaster, RNA interference, Small interfering RNA, Viral infection, dsRNA, Animals, Drosophila, Gene Expression Regulation, Host-Pathogen Interactions, RNA Interference, RNA, Double-Stranded, RNA, Small Interfering, RNA, Viral